Hepatoprotective Activity of Aqueous Extract of Rhyncosia Beddomei Baker Leaves Against Ethanol Induced Hepatotoxicity

The present work was carried out to investigate the hepatoprotective activity of aqueous extract of Rhyncosia beddomei Baker leaves in ethanol induced hepatotoxicity. The activity was evaluated against ethanol induced hepatotoxicity through monitoring liver function tests through the measurement of serum enzymes like SGOT SGPT and ALP, total proteins, total bilirubin, triglycerides and liver weight. The extract showed significant hepatoprotective activity at 200mg and 400mg/kg b.w by decreasing the levels of SGPT, SGOT, ALP, total bilirubin, triglycerides and increasing the total proteins when compared to positive control group. The results of the present study indicated that aqueous extract of Rhyncosia beddomei Baker has components that posses significant hepatoprotective potential.