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A short review on leptospirosis: Clinical manifestations, diagnosis and treatment

TitleA short review on leptospirosis: Clinical manifestations, diagnosis and treatment
Publication TypeJournal Article
Year of Publication2021
AuthorsChacko, C. S., L. S. Shravya, A. Jayakumar, S. L. Binu, R. D. Pant, A. Giri, S. Chand, and U. P. Nandakumar
JournalClinical Epidemiology and Global Health
Pagination100741
ISBN Number2213-3984
KeywordsCollege of Pharmaceutical Sciences, Scopus, WoS
Abstract

In the last few decades, leptospirosis has emerged globally as a fatal infectious disease. Yet, an understanding of the pathogenesis of leptospirosis continues to remain within the grey areas of scientific evidence. In a majority of the cases, the infections are asymptomatic. The benchmark test for leptospirosis is the microscopic agglutination test, commonly known as the MAT test. The standard of treatment is oral doxycycline, although penicillin and azithromycin can also be used. In this review, we aim to elaborately discuss the symptoms, diagnosis and the approved therapeutic regimen of leptospirosis.

URLhttps://www.sciencedirect.com/science/article/pii/S2213398421000452?via%3Dihub
DOI10.1016/j.cegh.2021.100741